(i) OKT-3 is used to prevent graft rejection following kidney transplantation.

Question

Give reasons for the following:

(i) OKT-3 is used to prevent graft rejection following kidney transplantation.

(ii) Kappa casein is involved in micelle stabilization of milk proteins.

(iii)Whey protein detoxifies xenobiotics.

(iv) Curd is used as pro-biotic.

(v) BCAA enriched food is taken before and after exercise.

Answer 1

(i) OKT-3 is monab-CD3 an immunosuppressant drug given intravenously to reverse acute rejection.

(ii) kappa casein contains a lipid molecule. 2/3 of the protein is hydrophobic

(iii) Whey protein results in elevation of a tripeptide glutathione in cells which detoxifies xenobiotics.

(iv) Curd is a good source of beneficial bacteria which can colonise the intestinal tract.

(v) BCAA is an essential for biosynthesis of muscle proteins as its carbon part is used as fuel and nitrogen converts into Alanine which changes into glucose in liver.