A local variable in Python is a variable that is defined within a function or block of code. It can only be accessed within that function or block of code, and once the function or block is exited, the local variable is destroyed.
A global variable in Python is a variable that is defined outside of any function or block of code. It can be accessed from anywhere within the code, including within functions.
The main difference between local and global variables is that local variables are only accessible within the function or block of code where they are defined, while global variables can be accessed from anywhere in the code.